Nicotinamide Riboside Chloride
Nicotinamide riboside chloride is a stable supplemental form of nicotinamide riboside (NR), a form of vitamin B3 that the body can use to produce NAD+ (nicotinamide adenine dinucleotide).
NAD+ is found in every cell and is involved in cellular energy production, DNA repair and normal metabolic function. Interest in NR has grown because NAD+ levels can decline with age and during periods of increased metabolic stress.
NAD+ and Cellular Energy
NAD+ plays an important role inside the mitochondria, where nutrients from food are converted into usable cellular energy.
It acts as a coenzyme in reactions involved in processing carbohydrates, fats and amino acids, helping cells maintain normal energy metabolism.
By providing a precursor for NAD+ production, nicotinamide riboside is commonly included in supplements focused on mitochondrial function, energy and healthy ageing.
Cellular Maintenance and Healthy Ageing
NAD+ is also required by enzymes involved in DNA repair, cellular stress responses and metabolic regulation.
These processes have made NAD+ metabolism an important area of healthy-ageing research. Nicotinamide riboside has been shown to raise NAD+ levels in humans, although research is still developing around exactly how this translates into long-term health outcomes.
Its most appropriate role is therefore as nutritional support for cellular energy and normal metabolic function, rather than as an anti-ageing treatment.
Mitochondrial and Metabolic Support
Mitochondria depend on a steady supply of NAD+ to carry out many of the reactions involved in ATP production.
Maintaining healthy NAD+ metabolism may therefore be particularly relevant in tissues with high energy demands, including the brain, heart and muscles.
NR is often paired with nutrients such as CoQ10, L-carnitine, magnesium and antioxidants in formulas designed to provide broader support for cellular and mitochondrial function.
Nicotinamide Riboside for Pets
Nicotinamide riboside can also be included in nutritional formulas for dogs and cats aimed at cellular energy, mitochondrial function and healthy ageing.
Its role as an NAD+ precursor makes it particularly relevant to formulations supporting older animals or pets with increased energy demands. Research specifically in companion animals is still developing, so it is best used as part of a balanced multi-ingredient formula at appropriate species-specific amounts.
Nicotinamide Riboside in O2B Products
At O2B Healthy, nicotinamide riboside is used in O2B MitoCell+, as well as our O2B K9+ MitoCell formulas for small, medium, large and extra-large dogs and O2B Feline+ MitoCell for cats. As a precursor to NAD+, nicotinamide riboside complements ingredients such as NAC, quercetin, resveratrol, active folate and vitamin B12 to support mitochondrial function, cellular energy metabolism, antioxidant defence and healthy ageing.